Geographic atrophy (GA) is characterized by the progressive death of retinal cells, particularly in the macula, which is essential for high-resolution vision. As these cells deteriorate, the ability to see fine details gradually diminishes. As GA advances, it leads to distinct areas of retinal damage, giving rise to the term "geographic," as these patches often appear map-like on the retina. Unlike wet AMD, which involves abnormal blood vessel growth and leakage beneath the retina, GA occurs without this extra growth. Instead, it involves the slow and irreversible loss of retinal tissue, primarily affecting central vision.
Globally, the prevalence of GA is expected to rise as the population ages, with the condition being most common in people aged 65 and older. Studies suggest that around 5-10% of individuals with dry AMD (the more common, non-neovascular form of age-related macular degeneration) may develop geographic atrophy as the disease progresses.
Although there is currently no cure, we are dedicated to advancing regenerative therapeutics aimed at halting or even reversing the effects of macular degeneration, including geographic atrophy. Our mission—restoring vision through regenerative medicine—drives our pursuit of innovative treatments that can provide hope for those affected by this debilitating condition.
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